Genotoxicity investigation of ELF-magnetic fields in Salmonella typhimurium with the sensitive SOS-based VITOTOX test
✍ Scribed by Luc Verschaeve; Roel Anthonissen; Magda Grudniewska; Jakub Wudarski; Lieven Gevaert; Annemarie Maes
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 566 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0197-8462
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✦ Synopsis
Abstract
We performed a genotoxicity investigation of extremely low‐frequency (ELF) magnetic fields (MFs, 50 Hz, 100 and 500 µT, 1 and 2 h exposure) alone and in combination with known chemical mutagens using the VITOTOX test. This test is a very sensitive reporter assay of Salmonella typhimurium bacteria based on the SOS response. Our study showed that ELF‐MFs do not induce SOS‐based mutagenicity in S. typhimurium bacteria and do not show any synergetic effect when combined with chemical mutagens. Bioelectromagnetics 32:580–584, 2011. © 2011 Wiley‐Liss, Inc.