The widely used herbicide paraquat was evaluated for genotoxicity in peripheral blood human lymphocyte cultures. Sister-chromatid exchanges (SCE), chromosome aberrations (CA), and micronuclei (MN) were scored as genetic endpoints. Paraquat was administered either alone or in combination with an exte
Genotoxicity evaluation of the tricyclic antidepressants amitriptyline and imipramine using human lymphocyte cultures
β Scribed by Saxena, Renu ;Ahuja, Y. R.
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 1988
- Weight
- 502 KB
- Volume
- 12
- Category
- Article
- ISSN
- 0192-2521
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The genotoxicity of humic acid and its possible interaction with the herbicides alachlor and maleic hydrazide have been evaluated in cultured human lymphocytes from two donors. Humic acid and the two herbicides have been tested (alone and combined) for sister-chromatid exchange (SCE) induction. In a
Chromosomal aberrations are associated with can-dium arsenite and hydroquinone, agents that have cer, birth defects, and pregnancy loss. Previous been reported to have relatively weak aneuploidystudies using banding techniques have revealed inducing and clastogenic activity. Significant inthat chrom