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Genotoxicity assessment of Garcinia achachairu Rusby (Clusiaceae) extract in mammalian cells in vivo

✍ Scribed by Eduardo de Souza Marques; Suellen Silva; Rivaldo Niero; Sérgio Faloni de Andrade; Paulo Cesar Pires Rosa; Fabio Ferreira Perazzo; Edson Luis Maistro

Book ID
116645909
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
368 KB
Volume
142
Category
Article
ISSN
0378-8741

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## Abstract The potential use of oxirane (epoxy) monomers in dental composite development raises the concern to test their genetic safety. Oxiranes can interact with DNA resulting in DNA damage, mutations, and possibly carcinogenesis. Our objective was to evaluate DNA damage and cell‐cycle disrupti