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Genotoxicity and immunogenicity of DNA-advanced glycation end products formed by methylglyoxal and lysine in presence of Cu2+

✍ Scribed by Saheem Ahmad; Moinuddin; Kiran Dixit; Uzma Shahab; Khursheed Alam; Asif Ali

Book ID: 116301585
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 627 KB
Volume: 407
Category: Article
ISSN: 0006-291X
DOI: 10.1016/j.bbrc.2011.03.064

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## Abstract Sugars and sugar degradation products are formed during food processing, but also endogenously __in vivo__. __In vitro__, nucleosides and DNA react readily with these carbonyl compounds during the formation of the two diastereomers of __N__^2^‐carboxyethyl‐2′‐deoxyguanosine (CEdG~A,B~),