## ABSTRACT A significant level of reactive oxygen species generation was observed in sodium fluoride (NaF) treated mouse bone marrow cells (BMCs). Reduced glutathione (GSH) as a free radical scavenger could be an important determining factor in Fβinduced genotoxicity. We therefore attempted to mon
Genotoxic Evaluation of Sodium Fluoride and Sodium Perborate in Mouse Bone Marrow Cells
β Scribed by N. Velazquez-Guadarrama; E. Madrigal-Bujaidar; D. Molina; G. Chamorro
- Publisher
- Springer
- Year
- 2005
- Tongue
- English
- Weight
- 343 KB
- Volume
- 74
- Category
- Article
- ISSN
- 0007-4861
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## ABSTRACT Treatment of mice with 15βmg l^β1^ sodium fluoride (NaF) for 30βdays increased the number of cell death, chromosomal aberrations (CAs) and βcells with chromatid breaksβ (aberrant cells) compared with control. The present study was intended to determine whether the fluoride (F)βinduced g