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Genotoxic effects and metabolism of 5-methoxypsoralen in yeast

✍ Scribed by E. Morichetti; R. Del Carratore; E. Cundari; C. Ceragioli; G. Bronzetti

Book ID
113252059
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
181 KB
Volume
234
Category
Article
ISSN
0165-1161

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## Abstract Several forms of cytochrome P‐450 (CYP) metabolize __R,S__‐warfarin in a regio‐ and enantioselective manner, therefore __R,S__‐warfarin can be recognized as a metabolic probe for a number of CYP isoforms. We have applied a warfarin model __in vivo__ in order to estimate the inhibitory p