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Genomics approaches to drug discovery

✍ Scribed by John F. Reidhaar-Olson; Brian K. Rhees; Juergen Hammer

Publisher: John Wiley and Sons
Year: 2001
Tongue: English
Weight: 275 KB
Volume: 84
Category: Article
ISSN: 0730-2312
DOI: 10.1002/jcb.10072

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✦ Synopsis

New approaches to drug discovery have come about in recent years as a result of important advances in genomics and bioinformatics. The availability of genome-scale sequence data, the development of new tools for highthroughput gene expression monitoring, and improvements in the ability to analyze large data sets have revolutionized the ®eld. In this article, we discuss three applications of genomics data in the drug discovery process: target discovery, prodrug strategies, and vaccine development.

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