๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Genomically humanized mice: technologies and promises

โœ Scribed by Devoy, Anny; Bunton-Stasyshyn, Rosie K. A.; Tybulewicz, Victor L. J.; Smith, Andrew J. H.; Fisher, Elizabeth M. C.


Book ID
109953509
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
468 KB
Volume
13
Category
Article
ISSN
1471-0056

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Life Technologies promises $1,000 genome
โœ DeFrancesco, Laura ๐Ÿ“‚ Article ๐Ÿ“… 2012 ๐Ÿ› Nature Publishing Group ๐ŸŒ English โš– 694 KB
CYP3A4 and pregnane X receptor humanized
โœ Frank J. Gonzalez ๐Ÿ“‚ Article ๐Ÿ“… 2007 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 206 KB

## Abstract Marked species differences exist in P450 expression and activities. In order to produce mouse models that can be used to more accurately predict human drug and carcinogen metabolism, P450โ€ and xenobiotic receptor humanized mice are being prepared using bacterial artificial chromosomes (