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Genomic structure of the human β-PIX gene and its alteration in gastric cancer

✍ Scribed by Zhong-you Li; You-jie Wang; Jian-ping Song; Hideki Kataoka; Shigeto Yoshii; Chang-ming Gao; Ya-ping Wang; Jian-nong Zhou; Satoshi Ota; Masamitsu Tanaka; Haruhiko Sugimura

Book ID
117467197
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
204 KB
Volume
177
Category
Article
ISSN
0304-3835

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p14 ARF , generated through an alternative splicing process that replaces the first exon, 1␣, of p16 INK4a with exon 1␤, located >15 kb upstream of exon 1␣, has been shown to function as a growth suppressor. We examined 11 gastric cancer cell lines for mRNA expression, homozygous deletion, mutation,