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Genomic structure and promoter activity of the human tissue factor pathway inhibitor-2 gene

✍ Scribed by Shintaro Kamei; Yoshiaki Kazama; Joseph L. Kuijper; Donald C. Foster; Walter Kisiel


Book ID
114147286
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
784 KB
Volume
1517
Category
Article
ISSN
0167-4781

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## Abstract To identify tumor‐suppressor genes inactivated by aberrant methylation of promoter CpG islands (CGIs) in human malignant melanomas, genes upregulated by treatment of cells with a demethylating agent, 5‐aza‐2′‐deoxycytidine (5‐aza‐dC), were searched for using oligonucleotide microarrays