Genomic structure and chromosomal mapping of the mouse hic-5 gene that encodes a focal adhesion protein
โ Scribed by Jun'ichi Mashimo; Motoko Shibanuma; Hitoshi Satoh; Kazuhiro Chida; Kiyoshi Nose
- Book ID
- 117519849
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 310 KB
- Volume
- 249
- Category
- Article
- ISSN
- 0378-1119
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Hic-5 is a paxillin homologue with four LIM domains in its C-terminal region, localized mainly in focal adhesions in normal fibroblasts. Hic-5 is also known to associate with focal adhesion kinase (FAK) or the related CAKโค, and with vinculin. In the present study, we examined changes in Hic-5 and pa
Sequence analysis of cDNA products, derived from adult porcine testis mRNA, gave overlapping nucleotide sequence correlating to 1952โbp of the sperm adhesion molecule 1 (__SPAM1__) gene. This sequence was shown to be homologous to __SPAM1__ genes known in other mammalian species and contained an ope