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Genomic Organization of the Human ERM (ETV5) Gene, a PEA3 Group Member of ETS Transcription Factors

✍ Scribed by Didier Monté; Laurent Coutte; Frédérique Dewitte; Pierre-Antoine Defossez; Maryvonne Le Coniat; Dominique Stéhelin; Roland Berger; Yvan de Launoit

Book ID
115613299
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
255 KB
Volume
35
Category
Article
ISSN
0888-7543

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The PEA3 group of transcription factors belongs to the ets family and is composed of 3 known members, PEA3, ERM and ER81, which are more than 95% identical within the DNAbinding ETS domain and exhibit 50% aa identity overall. Recently, transgenic mice bearing the c-erbB-2/neu oncogene have been show