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Genomic organization, comparative analysis, and genetic polymorphisms of the bovine and ovine prion Doppel genes (PRND)

✍ Scribed by Sergio Comincini; Maria G. Foti; Michael A. Tranulis; David Hills; Giovanni Di Guardo; Gabriele Vaccari; John L. Williams; Ingrid Harbitz; Luca Ferretti


Publisher
Springer-Verlag
Year
2001
Tongue
English
Weight
424 KB
Volume
12
Category
Article
ISSN
0938-8990

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Analysis of polymorphic microsatellites
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## Summary Twenty‐four microsatellite sites with at least three repeats were found in the bovine prion protein gene (__PRNP__) and 23 in the ovine __PRNP__ gene. Eight microsatellite sites were polymorphic in cattle and six in sheep with up to 10 alleles per site. In many cases allelic DNA fragment