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Genomic integration and gene expression by a modified adenoviral vector

✍ Scribed by Zheng, Changyu; Baum, Bruce J.; Iadarola, Michael J.; O'Connell, Brian C.


Book ID
109827616
Publisher
Nature Publishing Group
Year
2000
Tongue
English
Weight
319 KB
Volume
18
Category
Article
ISSN
1087-0156

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Background The a v integrin is present in vascular endothelium, including that of the kidney. It is also upregulated in the presence of inΒ―ammatory cytokines and in some neoplasms. In an effort to transduce vascular endothelial cells, we compare in vitro and in vivo adenoviral gene transfer of a vec