Genomic instability induced by orthopaedic wear debris in cultured human fibroblasts
โ Scribed by Martin Figgitt; Roger Newson; Ian Leslie; John Fisher; Eileen Ingham; Charles Case
- Book ID
- 113934034
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 75 KB
- Volume
- 290
- Category
- Article
- ISSN
- 0300-483X
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The in vitro biocompatibility of six wear-resistant coatings that were devised as an alternative to polyethylene in resurfacing hip arthroplasties was assessed. The coatings were applied on glass-cover slips via the chemical vapour deposition (CVD) and physical vapour deposition (PVD) methods. Testi
## Abstract Titaniumโaluminumโvanadium wear particles isolated from the softโtissue membrane of a failed total hip arthroplasty were added to human fibroblasts in cell culture. The cellular response to particle challenge was determined by assaying for levels of interleukinโ1ฮฒ, interleukinโ6, tumor