Genomic instability, DNA methylation, and natural selection in colorectal carcinogenesis
β Scribed by Jarle Breivik; Gustav Gaudernack
- Book ID
- 112264954
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 238 KB
- Volume
- 9
- Category
- Article
- ISSN
- 1044-579X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Mounting evidence underlines the role of genomic hypomethylation in the generation of genomic instability (GI) and tumorigenesis, but whether DNA hypomethylation is required for hepatocellular carcinoma (HCC) development and progression remains unclear. We investigated the correlation b
The emergence of tumour cells resistant to chemotherapeutic treatment is a major confounding factor in anticancer treatment. Many chemotherapeutic drugs are DNA damaging agents. Resistance to DNA damage can be acquired via a plethora of different mechanisms, including, surprisingly, loss of DNA mism