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Genomic instability and increased expression of BUB1B and MAD2L1 genes in ductal breast carcinoma

✍ Scribed by Marina Scintu; Rita Vitale; Maria Prencipe; Antonietta Pia Gallo; Loriana Bonghi; Vanna Maria Valori; Evaristo Maiello; Monica Rinaldi; Emanuela Signori; Carla Rabitti; Massimo Carella; Bruno Dallapiccola; Vittorio Altomare; Vito M. Fazio; Paola Parrella

Book ID
116334444
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
795 KB
Volume
254
Category
Article
ISSN
0304-3835

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Expression of the death-related proteins (DRPs) Bcl-2, Bax, Bcl-x and Bak that regulate cell survival and death was examined using immuno-histochemical methods in a group of 142 T 1 (F2 cm) ductal breast carcinomas. Immunostaining results were correlated with loss of apoptosis and clinicopathologica