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Genomic instability and cancer: scanning the Caenorhabditis elegans genome for tumor suppressors

โœ Scribed by van Haaften, Gijs; Plasterk, Ronald HA; Tijsterman, Marcel


Book ID
110069078
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
271 KB
Volume
23
Category
Article
ISSN
0950-9232

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## Abstract The Inhibitor of Growth 1 (ING1) gene has been identified and characterized as a Typeโ€II tumor suppressor gene (TSG). Subsequently, 4 additional members of the family were identified by homology search. ING proteins contain a nuclear localization sequence (NLS) and a plant homeo domain