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Genomic imprinting in germ cells: imprints are under control

✍ Scribed by Arnaud, Philippe

Book ID: 115476322
Publisher: Bioscientifica
Year: 2010
Tongue: English
Weight: 258 KB
Volume: 140
Category: Article
ISSN: 1470-1626
DOI: 10.1530/rep-10-0173

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## BACKGROUND. Insulin-like growth factor-2 (IGF2) and H19 are reciprocally imprinted genes on chromosome 11; IGF2 is expressed paternally and H19 is expressed maternally. Loss of imprinting (LOI) at both H19 and IGF2 has been reported in seven fully informative adult testicular germ cell tumors (