Genomic imprinting and human hereditary disorders
โ Scribed by M. V. Nemtsova
- Book ID
- 110669727
- Publisher
- SP MAIK Nauka/Interperiodica
- Year
- 2000
- Tongue
- English
- Weight
- 794 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0026-8933
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๐ SIMILAR VOLUMES
Activation of the silent maternal ICF2 allele has recently been found in approximately half of Wilms'tumour (WTs) examined. This process of imprint relaxation leads to biallelic expression of ICF2 and it has been suggested that this is a key event in the onset of some WTs. Although it has previously
The existence of functional differences between parts of the maternal and paternal genome has been demonstrated. The control of gene expression through genomic imprinting plays a significant role in normal developmental processes in mammals and is also instrumental in several human pathological cond