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Genomic imbalances associated with mullerian aplasia

✍ Scribed by Cheroki, C; Krepischi-Santos, A C V; Szuhai, K; Brenner, V; Kim, C A E; Otto, P A; Rosenberg, C


Book ID
118748448
Publisher
BMJ Publishing Group
Year
2007
Tongue
English
Weight
700 KB
Volume
45
Category
Article
ISSN
0022-2593

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## Abstract The expression of the chimeric __BCR/ABL1__ fusion gene resulting from t(9;22)(q34;q11) in chronic myelogenous leukemia (CML) is necessary for malignant transformation, but not sufficient to maintain disease progression. The appearance of various chromosomal and molecular alterations in