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Genomic heterogeneity and instability of the AZF locus on the human Y chromosome

✍ Scribed by Peter H. Vogt

Book ID
116733587
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
606 KB
Volume
224
Category
Article
ISSN
0303-7207

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## Abstract The gonadoblastoma (GBY) locus is the only oncogenic locus on the human Y chromosome. It is postulated to serve a normal function in the testis, but could exert oncogenic effects in dysgenetic gonads of individuals with intersex and/or dysfunctional testicular phenotypes. Recent studies