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Genomic Editing Tools to Model Human Diseases with Isogenic Pluripotent Stem Cells

✍ Scribed by Kim, Huen Suk; Bernitz, Jeffrey M.; Lee, Dung-Fang; Lemischka, Ihor R.

Book ID
126454240
Publisher
Mary Ann Liebert
Year
2014
Tongue
English
Weight
954 KB
Volume
23
Category
Article
ISSN
1547-3287

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In the past few years, cellular programming, whereby virtually all human cell types, including those deep within the brain or internal organs, can potentially be produced and propagated indefinitely in culture, has opened the door to a new type of disease modeling. Importantly, many diseases or dise