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Genomic copy-number alterations of MYC and FHIT genes are associated with survival in esophageal squamous-cell carcinoma

✍ Scribed by Yutaka Miyawaki; Hiroshi Kawachi; Akishi Ooi; Yoshinobu Eishi; Tatsuyuki Kawano; Johji Inazawa; Issei Imoto

Book ID: 114703303
Publisher: John Wiley and Sons
Year: 2012
Tongue: English
Weight: 575 KB
Volume: 103
Category: Article
ISSN: 1347-9032
DOI: 10.1111/j.1349-7006.2012.02329.x

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## Abstract The genes __CDKN2B (MTS2__) and __CDKN2 (MTSI)__ encoding the proteins p15 and p16 are both located on chromosomal band 9p21, a locus at which frequent homozygous and heterozygous deletions occur in many primary human tumors, including esophageal carcinoma. __CDKN2__ and __CDKN2B__ belo