Genomic Convergence of Genome-wide Investigations for Complex Traits
β Scribed by Georgios D. Kitsios; Elias Zintzaras
- Book ID
- 111111511
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 100 KB
- Volume
- 73
- Category
- Article
- ISSN
- 0003-4800
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For most human complex diseases and traits, SNPs identified by genome-wide association studies (GWAS) explain only a small fraction of the heritability. Here we report a user-friendly software tool called genome-wide complex trait analysis (GCTA), which was developed based on a method we recently de
## Abstract Genomeβwide association studies of discrete traits generally use simple methods of analysis based on Ο^2^ tests for contingency tables or logistic regression, at least for an initial scan of the entire genome. Nevertheless, more power might be obtained by using various methods that anal