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Genomic acute myeloid leukemia-associated inv(16)(p13q22) breakpoints are tightly clustered

✍ Scribed by van der Reijden, Bert A; Dauwerse, Hans G; Giles, Rachel H; Jagmohan-Changur, Shantie; Wijmenga, Cisca; Liu, P Paul; Smit, Bep; Wessels, Hans W; Beverstock, Geoff C; Jotterand-Bellomo, Martine


Book ID
110061778
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
397 KB
Volume
18
Category
Article
ISSN
0950-9232

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FISH identifies inv(16)(p13q22) masked b
✍ Judith Dierlamm; Michel Stul; Hilde Vranckx; Lucienne Michaux; Danielle E. M. Ol πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 600 KB

The inv(16)(p13q22) masked by different translocations was detected by fluorescence in situ hybridization (FISH) and confirmed by molecular analysis in three adult patients presenting with acute myeloid leukemia (AML)-M2 (cases 1 and 3) and M4Eo (case 2). Cytogenetic analysis revealed 47,XX,t(9;16)(