Genomewide Association Studies and Common Disease — Realizing Clinical Utility
✍ Scribed by Fugger, Lars; McVean, Gil; Bell, John I.
- Book ID
- 118158773
- Publisher
- Massachusetts Medical Society
- Year
- 2012
- Tongue
- English
- Weight
- 340 KB
- Volume
- 367
- Category
- Article
- ISSN
- 0096-6762
No coin nor oath required. For personal study only.
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## Abstract In genomewide genetic association studies, prior biological knowledge may help distinguish variation that is truly associated with a quantitative trait from the vast majority of unassociated variation that may be significant in hypothesis testing due to chance. However, formal methods f
## Abstract Genomewide association studies are an exciting strategy in genetics, recently becoming feasible and harvesting many novel genes linked to multiple phenotypes. Determining the significance of results in the face of testing a genomewide set of multiple hypotheses, most of which are produc