Genome-wide TDT analysis in a localized population with a high prevalence of multiple sclerosis indicates the importance of a region on chromosome 14q

A widely expressed transcription factor

A widely expressed transcription factor with multiple DNA sequence specificity, CTCF, is localized at chromosome segment 16q22.1 within one of the smallest regions of overlap for common deletions in breast and prostate cancers

✍ Galina N. Filippova; Annika Lindblom; Linda J. Meincke; Elena M. Klenova; Paul E 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 200 KB 👁 2 views

The cellular protooncogene MYC encodes a nuclear transcription factor that is involved in regulating important cellular functions, including cell cycle progression, differentiation, and apoptosis. Dysregulated MYC expression appears critical to the development of various types of malignancies, and t