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Genome-wide search for replicable risk gene regions in alcohol and nicotine co-dependence

✍ Scribed by Lingjun Zuo; Fengyu Zhang; Heping Zhang; Xiang-Yang Zhang; Fei Wang; Chiang-Shan R. Li; Lingeng Lu; Jiang Hong; Lin Lu; John Krystal; Hong-Wen Deng; Xingguang Luo


Book ID
111995343
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
406 KB
Volume
159B
Category
Article
ISSN
1552-4841

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✍ Reich, Theodore; Edenberg, Howard J.; Goate, Alison; Williams, Jeff T.; Rice, Jo πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 46 KB πŸ‘ 2 views

Alcohol dependence is a leading cause of morbidity and premature death. Several lines of evidence suggest a substantial genetic component to the risk for alcoholism: sibs of alcoholic probands have a 3-8 fold increased risk of also developing alcoholism, and twin heritability estimates of 50-60% are