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Genome-wide genetic marker discovery and genotyping using next-generation sequencing

✍ Scribed by Davey, John W.; Hohenlohe, Paul A.; Etter, Paul D.; Boone, Jason Q.; Catchen, Julian M.; Blaxter, Mark L.

Book ID: 109953410
Publisher: Nature Publishing Group
Year: 2011
Tongue: English
Weight: 831 KB
Volume: 12
Category: Article
ISSN: 1471-0056
DOI: 10.1038/nrg3012

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## Abstract A simple approach to design and analysis of genome‐wide linkage scans is described, based on an approximation to the joint distribution of likelihood ratio statistics at a large number of single nucleotide polymorphism (SNP) loci. The approximation is readily calculated and makes it fea