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Genome-wide CNV analysis in mouse induced pluripotent stem cells reveals dosage effect of pluripotent factors on genome integrity

โœ Scribed by Chen, Yulin; Guo, Lin; Chen, Jiekai; Zhao, Xiangjie; Zhou, Weichen; Zhang, Cheng; Wang, Jiucun; Jin, Li; Pei, Duanqing; Zhang, Feng


Book ID
121556874
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
347 KB
Volume
15
Category
Article
ISSN
1471-2164

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## Abstract While lipopolysaccharides (LPS) induce dendritic cell (DC) maturation and migration to lymph nodes, glucocorticoids such as dexamethazone (Dex) have a profound suppressive effect on immune response. The mechanisms that might control this suppressive effect of Dex have been extensively i