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Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

✍ Scribed by Rioux, John D; Xavier, Ramnik J; Taylor, Kent D; Silverberg, Mark S; Goyette, Philippe; Huett, Alan; Green, Todd; Kuballa, Petric; Barmada, M Michael; Datta, Lisa Wu


Book ID
109919555
Publisher
Nature Publishing Group
Year
2007
Tongue
English
Weight
543 KB
Volume
39
Category
Article
ISSN
1061-4036

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✍ Mark Tremelling; Miles Parkes πŸ“‚ Article πŸ“… 2007 πŸ› John Wiley and Sons 🌐 English βš– 97 KB πŸ‘ 1 views

The last 12 months have seen unprecedented progress in identifying the susceptibility genes that predispose to common disease in general and Crohn's disease in particular. Success has derived from the new technique of genome-wide association scanning in large panels of cases and controls. This has i