Genome wide association studies in presence of misclassified binary responses
β Scribed by Smith, Shannon; Hay, El; Farhat, Nourhene; Rekaya, Romdhane
- Book ID
- 121578988
- Publisher
- BioMed Central
- Year
- 2013
- Tongue
- English
- Weight
- 444 KB
- Volume
- 14
- Category
- Article
- ISSN
- 1471-2156
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Though multiple interacting loci are likely involved in the etiology of complex diseases, early genomeβwide association studies (GWAS) have depended on the detection of the marginal effects of each locus. Here, we evaluate the power of GWAS in the presence of two linked and potentially
## Abstract Genomeβwide caseβcontrol association study is gaining popularity, thanks to the rapid development of modern genotyping technology. In such studies, population stratification is a potential concern especially when the number of study subjects is large as it can lead to seriously inflated