Recently, genome-wide association studies have substantially expanded our knowledge about genetic variants that influence the susceptibility to complex diseases. Although standard statistical tests for each single-nucleotide polymorphism (SNP) separately are able to capture main genetic effects, dif
Genome-wide association studies in economics and entrepreneurship research: promises and limitations
✍ Scribed by Philipp D. Koellinger; Matthijs J. H. M. van der Loos; Patrick J. F. Groenen; A. Roy Thurik; Fernando Rivadeneira; Frank J. A. van Rooij; André G. Uitterlinden; Albert Hofman
- Publisher
- Springer US
- Year
- 2010
- Tongue
- English
- Weight
- 410 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0921-898X
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Genome wide association studies (GWAS) have revealed many fascinating insights into complex diseases even from simple, single-marker statistical tests. Most of these tests are designed for testing of associations between a phenotype and an autosomal genotype and are therefore not applicable to X chr
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