Genome-wide analysis of loss of heterozygosity and copy number amplification in uterine leiomyomas using the 100K single nucleotide polymorphism array
β Scribed by Kellen L. Meadows; Danica M.K. Andrews; Zongli Xu; Gleta K. Carswell; Shannon K. Laughlin; Donna D. Baird; Jack A. Taylor
- Book ID
- 113956743
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- English
- Weight
- 329 KB
- Volume
- 91
- Category
- Article
- ISSN
- 0014-4800
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## Abstract We have undertaken an extensive highβresolution analysis of loss of heterozygosity (LOH) in 30 high grade gliomas using the Affymetrix 100K SNP mapping array. Only 70% of LOH events were accompanied by a copy number loss (CNA~loss~), and of the other 30%, the distal region of 17p prefer
## Abstract Deletion of the long arm of chromosome 20 is a common abnormality associated with myeloid malignancies. We characterized abnormalities of chromosome 20 as defined by metaphase cytogenetics (MC) in patients with myeloid neoplasms to define commonly deleted regions (CDR) and commonly reta