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Genome-wide analysis of DNA methylation identifies novel cancer-related genes in hepatocellular carcinoma

โœ Scribed by Shitani, Masahiro; Sasaki, Shigeru; Akutsu, Noriyuki; Takagi, Hideyasu; Suzuki, Hiromu; Nojima, Masanori; Yamamoto, Hiroyuki; Tokino, Takashi; Hirata, Koichi; Imai, Kohzoh; Toyota, Minoru; Shinomura, Yasuhisa

Book ID
118302762
Publisher
S. Karger AG
Year
2012
Tongue
English
Weight
383 KB
Volume
33
Category
Article
ISSN
1010-4283

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Genome-wide copy number analyses identif
Genome-wide copy number analyses identified novel cancer genes in hepatocellular carcinoma
โœ Deshui Jia; Lin Wei; Weijie Guo; Ruopeng Zha; Meiyan Bao; Zhiao Chen; Yingjun Zh ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 874 KB

A powerful way to identify driver genes with causal roles in carcinogenesis is to detect genomic regions that undergo frequent alterations in cancers. Here we identified 1,241 regions of somatic copy number alterations in 58 paired hepatocellular carcinoma (HCC) tumors and adjacent nontumor tissues