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Genome Scan of Human Systemic Lupus Erythematosus: Evidence for Linkage on Chromosome 1q in African-American Pedigrees

✍ Scribed by Kathy L. Moser, Barbara R. Neas, Jane E. Salmon, Hua Yu, Courtney Gray-McGuire, Neeraj Asundi, Gail R. Bruner, Jerome Fox, Jennifer Kelly, Stephanie Henshall, Debra Bacino, Myron Dietz, Robert Hogue, Gerald Koelsch, Lydia Nightingale, Tim Shaver, Nabih I. Abdou, Daniel A. Albert, Craig Carson, Michelle Petri, Edward L. Treadwell, Judith A. James and John B. Harley

Book ID: 123641694
Publisher: National Academy of Sciences
Year: 1998
Tongue: English
Weight: 917 KB
Volume: 95
Category: Article
ISSN: 0027-8424
DOI: 10.2307/46636

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## Abstract ## Objective To identify chromosome regions likely to harbor genes that predispose to the development of systemic lupus erythematosus (SLE) by analyzing a full genome scan in nuclear families ascertained for siblings with SLE. ## Methods Approximately 400 multiallelic markers spaced