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Genome-scale models of metabolism and gene expression extend and refine growth phenotype prediction

✍ Scribed by O{middle dot}Brien, E. J.; Lerman, J. A.; Chang, R. L.; Hyduke, D. R.; Palsson, B. O.


Book ID
121326881
Publisher
Nature Publishing Group
Year
2013
Tongue
English
Weight
748 KB
Volume
9
Category
Article
ISSN
1744-4292

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## Abstract ## Background A model for __in vivo__ gene therapy based on electroporation of human growth hormone (hGH)‐coding naked DNA in the muscle of dwarf (lit/lit) and immunodeficient dwarf (lit/scid) mice is described. ## Methods A plasmid containing the ubiquitin C promoter and the genomic