β Scribed by Rippe, Karsten
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By Way Of Its Clear And Logical Structure, As Well As Abundant Highresolution Illustrations, This Is A Systematic Survey Of The Players And Pathways That Control Genome Function In The Mammalian Cell Nucleus. As Such, This Handbook And Reference Ties Together Recently Gained Knowledge From A Variety Of Scientific Disciplines And Approaches, Dissecting All Major Genomic Events: Transcription, Replication, Repair, Recombination And Chromosome Segregation. A Special Emphasis Is Put On Transcriptional Control, Including Genome-wide Interactions And Non-coding Rnas, Chromatin Structure, Epigenetics And Nuclear Organization. With Its Focus On Fundamental Mechanisms And The Associated Biomolecules, This Will Remain Essential Reading For Years To Come. Front Matter -- Deciphering Dna Sequence Information / Mark Kaganovich, Michael Snyder -- Dna Methylation / Carina Frauer, Fabio Spada, Heinrich Leonhardt -- Nucleosomes As Control Elements For Accessing The Genome / Mekonnen Lemma Dechassa, Karolin Luger -- Histone Modifications And Their Role As Epigenetic Marks / Karl Nightingale -- Chromatin Remodeling And Nucleosome Positioning / Gernot LΜngst, Vladimir B Teif, Karsten Rippe -- The Folding Of The Nucleosome Chain / Karsten Rippe -- The Crowded Environment Of The Genome / Ron Hancock -- The Nuclear Lamina As A Chromatin Organizer / Nikolaj Zuleger, Eric C Schirmer -- Three-dimensional Architecture Of Genomes / Job Dekker -- Transcriptional Initiation: Frequency, Bursting, And Transcription Factories / Kieran Finan, Peter R Cook -- Processing Of Mrna And Quality Control / Ute Schmidt, Edouard Bertrand -- The Nucleolus / Saskia Hutten, Belinda J Westman, FraαΉ ois-michel Boisvert, Silvana Van Koningsbruggen, Angus I Lamond -- Non-coding Rnas As Regulators Of Transcription And Genome Organization / Katalin Fejes TΜ€th, Gregory Hannon -- Rna Networks As Digital Control Circuits Of Nuclear Functions / John S Mattick -- Dna Replication And Inheritance Of Epigenetic States / Armelle Corpet, GenevΓ―ve Almouzni -- Interplay And Quality Control Of Dna Damage Repair Mechanisms / Berina Eppink, Jeroen Essers, Roland Kanaar -- Higher Order Chromatin Organization And Dynamics / Hilmar Strickfaden, Thomas Cremer, Karsten Rippe -- The Mitotic Chromosome: Structure And Mechanics / John F Marko -- Meiotic Chromosome Dynamics / Nancy Kleckner, Liangran Zhang, Beth Weiner, Denise Zickler -- Understanding Genome Function: Quantitative Modeling Of Chromatin Folding And Chromatin-associated Processes / Mariliis Tark-dame, Martijn S Luijsterburg, Dieter W Heermann, Roel Van Driel -- Index. Edited By Karsten Rippe. Includes Bibliographical References And Index.
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By Way Of Its Clear And Logical Structure, As Well As Abundant Highresolution Illustrations, This Is A Systematic Survey Of The Players And Pathways That Control Genome Function In The Mammalian Cell Nucleus. As Such, This Handbook And Reference Ties Together Recently Gained Knowledge From A Variety