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Genome biology: New family of DNA molecule found in mammals

✍ Scribed by Casci, Tanita


Book ID
111883682
Publisher
Nature Publishing Group
Year
2012
Tongue
English
Weight
137 KB
Volume
13
Category
Article
ISSN
1471-0056

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## Abstract The mechanism of action of ZR2002, a chimeric amino quinazoline designed to possess mixed EGFR tyrosine kinase (TK) inhibitory and DNA targeting properties, was compared to those of ZR01, a reversible inhibitor of the same class and PD168393, a known irreversible inhibitor of EGFR. ZR20