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Genome and gene alterations by insertions and deletions in the evolution of human and chimpanzee chromosome 22

✍ Scribed by Natalia Volfovsky; Taras K Oleksyk; Kristine C Cruz; Ann L Truelove; Robert M Stephens; Michael W Smith

Book ID
115003088
Publisher
BioMed Central
Year
2009
Tongue
English
Weight
394 KB
Volume
10
Category
Article
ISSN
1471-2164

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## Abstract Recurrent deletions of chromosome fragments observed in neoplasms are thought to participate in tumor development through the inactivation of tumor‐suppressor genes. In gliomas, the most frequent deletions involve chromosome arms 9p, 10q, 17p, 19q and 22q. We have analysed deletions of