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Genistein inhibits expression of vascular endothelial growth factor in HER-2/neu transfected human breast cancer MCF-7 cells

✍ Scribed by Jun-dong Zhu; Xiao-ping Yu; Man-tian Mi

Publisher: Chinese Anti-Cancer Association
Year: 2006
Tongue: English
Weight: 503 KB
Volume: 18
Category: Article
ISSN: 1000-9604
DOI: 10.1007/s11670-006-0083-0

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## Abstract Her‐2/__neu__ (__erb__B‐2) oncogene overexpression is associated with increased tumor progression and metastasis. Fatty acid synthase (FAS), the key lipogenic enzyme responsible for the endogenous synthesis of fatty acids, has been shown to be one of the genes regulated by Her‐2/__neu__