Methotrexate induction of human sulfotra
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Xinrong Chen; Sharon M. Baker; Guangping Chen
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Article
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2005
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John Wiley and Sons
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English
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Methotrexate (MTX) was the first antifolate drug developed for the treatment of cancer. It is also effective in treating inflammatory and autoimmune diseases. Sulfotransferases are phase II drug-metabolizing enzymes and their induction by hormones and endogenous molecules is relatively well known, a