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Genetics studies on the β subunit of Escherichia coli RNA polymerase

✍ Scribed by Nene, Vishvanath ;Glass, Robert E.

Publisher
Springer
Year
1984
Tongue
English
Weight
486 KB
Volume
196
Category
Article
ISSN
0026-8925

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✦ Synopsis

A single species of RNA polymerase is responsible for the transcription of genetic material in Escherichia coli; and, each component of this essential enzyme is encoded by a single gene. Nevertheless, we report the characterisation of a viable deletion mutant lacking about 165 bp in the region coding for residues 965 to 1143 of the beta subunit of this enzyme. The foreshortened beta polypeptide appears to function as normal, suggesting that this region is, in fact, non-essential with regard to the usual functions of E. coli RNA polymerase.

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