Genetics of the Costello syndrome
β Scribed by Lurie, Iosif W.
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 204 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0148-7299
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We present a lbyear-old girl with mental retardation, short stature, coarse face, unusually thick, loose skin of the hands and feet, deep plantar and palmar creases, and nasal papillomata. Her history and physical fmdings are compared to those of 2 children initially reported by Costello and to 1 ch
We report on a 6-year-old girl with Costello syndrome. Main manifestations included poor postnatal growth, relative macrocephaly, curly hair, distinct "coarse" face, mild mental retardation, happy and sociable personality, loose dark skin particularly of hands and feet, acanthosis nigricans, thin de