## Abstract Oxidative stress reactions may contribute to the pathogenesis of Parkinson's disease (PD). The superoxide dismutases potentially play significant roles in PD by detoxifying superoxide radical. We developed genomic DNA and cDNAβbased sequencing assays to identify genetic variants in the
Genetics of superoxide dismutase in apple
β Scribed by A. G. Manganaris; F. H. Alston
- Publisher
- Springer
- Year
- 1997
- Tongue
- English
- Weight
- 222 KB
- Volume
- 95
- Category
- Article
- ISSN
- 0040-5752
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We have studied genetic variation for levels of activity of the enzyme superoxide dismutase (SOD) in Drosophila melanogaster. We have constructed 34 lines homozygous for a given second and a given third chromosome derived from eight original lines; all lines were homozygous for the "fast" (F) allele
## Abstract ## Objective To examine the influence of superoxide on the severity of collagenβinduced arthritis (CIA) in mice. ## Methods CIA was induced in DBA/1J mice lacking the extracellular superoxide dismutase (ECβSOD) gene (knockout [KO]) and in normal DBA/1J mice (wildβtype [WT]). ## Resu