Biosynthesis of nisin in the subtilin pr
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Helena Rintala; Tytti Graeffe; Lars Paulin; Nisse Kalkkinen; Per E. J. Saris
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Article
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1993
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Springer Netherlands
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English
β 375 KB
Plasmids having the structural gene of nisin (nis A) combined with the subfilin or two hybrid subtilin-nisin leaders were integrated into the subtilin operon in the chromosome of a nisin-resistant and subtilin-producing strain of B. subtilis by single crossing over. Nisin was produced only when the