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Genetics of spike-wave discharges in the electroencephalogram (EEG) of the WAG/Rij inbred rat strain: A classical mendelian crossbreeding study

โœ Scribed by B. W. M. M. Peeters; J. M. L. Kerbusch; A. M. L. Coenen; J. M. H. Vossen; E. L. J. M. van Luijtelaar


Publisher
Springer US
Year
1992
Tongue
English
Weight
429 KB
Volume
22
Category
Article
ISSN
0001-8244

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CNQX, a new non-NMDA receptor antagonist
โœ G.M.J. Ramakers; B.W.M.M. Peeters; J.M.H. Vossen; A.M.L. Coenen ๐Ÿ“‚ Article ๐Ÿ“… 1991 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 330 KB

The effects on seizures, EEG and behavior of the non-NMDA receptor antagonist CNQX (6-cyano-7-nitroquinoxaline-2,3-dione), were studied in the WAG/Rij rat with absence epilepsy. Intracerebroventricular injections (10, 50, and 100 nmol/5 microliters CNQX) showed that CNQX decreases the number of spik