Protein synthesis by ribosomes from several cryptopleurine-resistant yeast mutants is also resistant to emetine and tubulosine. These mutants can be classified into two different types: Class I mutants which display high levels of resistance to emetine and tubulosine and Class II mutants that are on
Genetics of resistance to 4-aminopyrazolo-(3,4-d)-pyrimidine in Saccharomyces cerevisiae
โ Scribed by Pickering, W. R. ;Woods, R. A.
- Publisher
- Springer
- Year
- 1973
- Tongue
- English
- Weight
- 680 KB
- Volume
- 122
- Category
- Article
- ISSN
- 0026-8925
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The hyperresistance to 4-nitroquinoline-N-oxide (4-NQO) and formaldehyde (FA) of yeast strains transformed with the multi-copy plasmids pAR172 and pAR184, respectively, is due to the two genes, SNQ and SFA, which are present on these plasmids. Restriction analysis revealed the maximal size of SFA as
## Abstract magnified image The cyclocondensation of 5โhydroxyโpyrido[2,3โ__d__]pyrimidines **1** with malonates gives pyrano[2โฒ,3โฒ:4,5]โpyrido[2,3โ__d__]pyrimidines **2**. Nitration of **1** and reduction with zinc in the presence of carboxylic acids/anhydrides gave 2โalkyloxazolo[5โฒ,4โฒ:4,5]pyrid