Genetics of Parkinson's disease: What do mutations in DJ-1 tell us?

The role of pathogenic DJ-1 mutations in

The role of pathogenic DJ-1 mutations in Parkinson's disease

✍ Patrick M. Abou-Sleiman; Daniel G. Healy; Niall Quinn; Andrew J. Lees; Nicholas 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 71 KB 👁 1 views

Genetic analysis of “leucine-rich repeat

Genetic analysis of “leucine-rich repeat (LRR) and immunoglobulin (Ig) domain-containing, Nogo receptor-interacting protein-1 (LINGO1)” in two independent Chinese parkinson's disease populations

✍ Yih-Ru Wu; Eng-King Tan; Chiung-Mei Chen; Prakash M. Kumar; Guey-Jen Lee-Chen; S 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 98 KB 👁 1 views

## Abstract A large genome‐wide association study has shown that the “leucine‐rich repeat (LRR) and immunoglobulin (Ig) domain‐containing, Nogo receptor‐interacting protein‐1 (__LINGO1__) gene” is associated with an increased risk for essential tremor (ET) recently. Given the clinical phenotype ove